Searchable abstracts of presentations at key conferences in endocrinology

ea0090ep614 | Endocrine-related Cancer | ECE2023

Pan-endocrine cancer pattern of somatic mutations: Toward Genotype–Phenotype correlation and machine learning methods

Zhang Liang , Crona Joakim

Background: Neuroendocrine tumors (NETs) and Adrenocortical carcinomas (ACCs) are rare and heterogeneous tumors entities. Advanced NETs and ACC own poor prognosis with less than 40% of five-year survival. There is a need for improved biomarkers to predict disease prognosis and treatment sensitivity. A broad overview of NETs and ACC genetics has never been explored.Aim: To investigate genotype–phenotype correlations on a pan-endocrine cancer level wi...